Article

Inhibitors of oncogenic Kras specifically prime CTLA4 blockade to transcriptionally…

medRxiv · 2025 · Mahadevan, K. K.; Maldonado, A. S.; Li, B.; Bickert, A. A.; Perdyan, A.; Kumbhar, S. V.; Piya, S.; Sockwell, A. M.; Morse, S. J.; Arian, K.; Sugimoto, H.; Shalapour, S.; Hong, D. S.; Heffernan, T. P.; MAITRA, A.; Kalluri, R.

Key facts

Title Inhibitors of oncogenic Kras specifically prime CTLA4 blockade to transcriptionally reprogram Tregs and overcome resistance to suppress pancreas cancer
First author Mahadevan, K. K.; Maldonado, A. S.; Li, B.; Bickert, A. A.; Perdyan, A.; Kumbhar, S. V.; Piya, S.; Sockwell, A. M.; Morse, S. J.; Arian, K.; Sugimoto, H.; Shalapour, S.; Hong, D. S.; Heffernan, T. P.; MAITRA, A.; Kalluri, R.
Journal medRxiv
Published Jan 1, 2025
DOI 10.1101/2025.02.28.640711
Devices mentioned DEN000008, K022086, K802418
Product codes mentioned JCC, JCI, KIT, MVU, NDS, NJT, PPM, KIS

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  • 1–9 FDA submissions mentioned
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