WHO ICTRP trial

Repeated IPC ischemic preconditioning, RIPC, ischemic reperfusion injury…

NL-OMON29689 · Overview of Medical Research in the Netherlands (NL-OMON) · Recruiting

Key facts

Trial ID NL-OMON29689
Public title Repeated IPC ischemic preconditioning, RIPC, ischemic reperfusion injury, endothelial function, end-stage renal disease, flow-mediated dilation (FMD) ischemisch preconditioneren (IPC), herhaalde IPC, ischemisch reperfusie schade, endotheel functie, flow-gemedieerde dilatatie
Scientific title AN EXPLORATIVE STUDY TO ASSESS THE EFFECT OF REPEATED REMOTE ISCHEMIC PRECONDITIONING ON ENDOTHELIAL FUNCTION AND INNATE IMMUNE RESPONSES IN PATIENTS WITH END-STAGE RENAL DISEASE
Primary sponsor Radboudumc Nijmegen
Registry Overview of Medical Research in the Netherlands (NL-OMON)
Recruitment status Recruiting
Study type Interventional
Conditions To examine the effect of daily repeated ischemic preconditioning on brachial artery endothelial function (measured as FMD% before and after IRI) during 7 days in patients with chronic kidney disease. We will recruit 20 subjects with chronic…
Interventions Remote RIPC: 4 cycles of ischemia of the forearm by inflating a blood pressure cuff around the upper arm at 200 mmHg during 5 minutes followed by 5 minutes of reperfusion. This procedure will be performed daily during 7 days.
Registration date Jan 30, 2015
Target size 20
Secondary IDs NL4949;NTR5054;CMO regio Arnhem-Nijmegen : 2014-1344
Registry page onderzoekmetmensen.nl

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