WHO ICTRP trial

NEOVACC: A personalised DNA vaccine for patients with advanced lung cancer

ISRCTN11752949 · International Standard Randomised Controlled Trial Number (ISRCTN) · Recruiting

Key facts

Trial ID ISRCTN11752949
Public title NEOVACC: A personalised DNA vaccine for patients with advanced lung cancer
Scientific title Targeting non-small cell lung cancer with Doggybone personalised cancer DNA vaccines (dbPCV)
Primary sponsor University of Liverpool
Registry International Standard Randomised Controlled Trial Number (ISRCTN)
Recruitment status Recruiting
Study type Interventional
Phase Phase I
Countries United Kingdom;England
Conditions Non-small cell lung cancer (NSCLC) with PDL1 expression =50% which does not achieve tumour clearance with anti-PD1 treatment Cancer
Interventions The NEOVACC doggybone personalised cancer vaccines (dbPCV) will be administered by PharmaJet Stratis Needle-free injection system. Participants will receive a 2mg/ml dose of dbPCV in 2 divided doses of 0.5ml every 3 weeks for the first 24…
Registration date Aug 5, 2025
Target size 15
Secondary IDs Nil known;Nil known;UoL001847
Registry page isrctn.com

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Source: World Health Organization (WHO), International Clinical Trials Registry Platform (ICTRP) · Source date:

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