WHO ICTRP trial

Exploratory study of the effect of oral hygiene and circadian rhythm on oral…

DRKS00023366 · German Clinical Trials Register · Recruiting

Key facts

Trial ID DRKS00023366
Public title Exploratory study of the effect of oral hygiene and circadian rhythm on oral microbiota composition in healthy volunteers
Scientific title Exploratory study of the effect of oral hygiene and circadian rhythm on oral microbiota composition in healthy volunteers - OralCirc
Primary sponsor German Cancer Research Center (DKFZ)
Registry German Clinical Trials Register
Recruitment status Recruiting
Study type observational
Countries Germany
Conditions The aim is to analyse circadian oscillations of the oral microbiome, including F. nucleatum, and the effects of oral hygiene measures on the oral microbiome composition over time.
Interventions Group 1: After an initial “wash-in” phase, biological material will be collected from the oral cavity during two separate time blocks. In the initial phase (day 0-4), subjects are asked to brush their teeth regularly in the morning and…
Registration date Oct 20, 2020
Target size 20
Secondary IDs U1111-1259-6490
Registry page drks.de

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Source: World Health Organization (WHO), International Clinical Trials Registry Platform (ICTRP) · Source date:

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