WHO ICTRP trial
LAVA1207-001/LAVA1207-002 A Phase 1 and 2a open-label trial to evaluate the…
CTIS2024-515821-27-00 · EU Clinical Trials Information System · Not Recruiting
Key facts
| Trial ID | CTIS2024-515821-27-00 |
|---|---|
| Public title | LAVA1207-001/LAVA1207-002 A Phase 1 and 2a open-label trial to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and antitumor activity of LAVA-1207, a PSMA-targeting bispecific ?d-T cell engager, alone or with low dose interleukin-2 or Pembrolizumab, in patients with therapy refractory metastatic castration resistant prostate cancer |
| Scientific title | LAVA1207-001/LAVA1207-002 A Phase 1 and 2a open-label trial to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and antitumor activity of LAVA-1207, a PSMA-targeting bispecific ?d-T cell engager, alone or with low dose interleukin-2 or Pembrolizumab, in patients… |
| Primary sponsor | LAVA Therapeutics N.V. |
| Registry | EU Clinical Trials Information System |
| Recruitment status | Not Recruiting |
| Study type | Interventional clinical trial of medicinal product |
| Phase | Human pharmacology (Phase I): Yes Therapeutic exploratory (Phase II): Yes Therapeutic confirmatory - (Phase III): No Therapeutic use - (Phase IV): No |
| Countries | United States;Spain;Netherlands |
| Conditions | Prostate Cancer, Prostate Cancer MedDRA version: 27.0Level: PTClassification code: 10036909Term: Prostate cancer metastatic Class: 100000004864;Therapeutic area: Diseases [C] - Neoplasms [C04] |
| Interventions | Product Name: KEYTRUDA 25 mg/mL concentrate for solution for infusion, Product Code:PRD4323105, Pharmaceutical Form: SOLUTION FOR INFUSION, Other descriptive name: , Strength: , Product Name: , Product Code:PRD11446407, Pharmaceutical Form… |
| Registration date | Jul 24, 2024 |
| Target size | 180 |
| Secondary IDs | NCT05369000;2021-001789-39;LAVA1207-001;LAVA1207-002;KEYNOTE-F73 |
| Registry page | euclinicaltrials.eu |
At a glance
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Source: World Health Organization (WHO), International Clinical Trials Registry Platform (ICTRP) · Source date: