WHO ICTRP trial
A study of EnGeneIC Dream Vectors (EDV's) packaged with the chemotherapy…
ACTRN12625000203459 · Australian New Zealand Clinical Trials Registry (ANZCTR) · Recruiting
Key facts
| Trial ID | ACTRN12625000203459 |
|---|---|
| Public title | A study of EnGeneIC Dream Vectors (EDV's) packaged with the chemotherapy, E-EDV-D682 given simultaneously as non-targeted EDVs carrying an immune enhancer called EDV-GC, in participants with advanced epidermal growth factor expressing cancers whose disease has progressed after one or two treatment regimes, or where other standard therapies are not appropriate. (EGFR EDV-D682/GC Trial) |
| Scientific title | An open-label, multicenter, Phase I/IIa study assessing the safety and efficacy of EGFR targeted EDVsTM carrying cytotoxic drug PNU-159682 plus concurrent immunomodulatory adjuvant non-targeted EDVs carrying a-galactosyl ceramide in subjects with advanced EGFR-expressing cancers who have failed… |
| Primary sponsor | EnGeneIC Pty Limited |
| Registry | Australian New Zealand Clinical Trials Registry (ANZCTR) |
| Recruitment status | Recruiting |
| Study type | Interventional |
| Phase | Phase 1 / Phase 2 |
| Countries | Australia |
| Conditions | EGFR expressing solid tumors;Lung cancer (NSCLC and Mesothelioma);Bladder/Kidney cancer;Colorectal cancer;Triple negative breast cancer (TNBC);Pancreatic ductal adenocarcinoma (PDAC); EGFR expressing solid tumors Lung cancer (NSCLC and… |
| Interventions | This study is testing an experimental treatment for people with advanced cancer after the failure of first or second line therapy or for people who do not have other treatment options. The experimental treatment consists of a chemotherapy… |
| Registration date | Feb 20, 2025 |
| Target size | 160 |
| Secondary IDs | EGFR EDV-D682/GC Trial |
| Registry page | anzctr.org.au |
At a glance
- No Results available
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About WHO ICTRP trial registrations
The WHO ICTRP combines trial registrations from primary registries worldwide into a single searchable index. Contact and ethics-committee details are not shown here.
Source: World Health Organization (WHO), International Clinical Trials Registry Platform (ICTRP) · Source date: