WHO ICTRP trial

Predictive value of ABCB1 genotypes on dose adjustment of imatinib in patients…

ACTRN12606000117516 · Australian New Zealand Clinical Trials Registry (ANZCTR) · Not Recruiting

Key facts

Trial ID ACTRN12606000117516
Public title Predictive value of ABCB1 genotypes on dose adjustment of imatinib in patients with GIST (Gastro-Intestinal Stromal Tumour) and CML (Chronic Myeloid Leukaemia)
Scientific title Predictive value of ABCB1 genotypes on dose adjustment of imatinib in patients with GIST(Gastro-Intestinal Stromal Tumour) and CML (Chronic Myeloid Leukaemia)
Primary sponsor Investigator Initiated - A/Professor Howard Gurney and Dr Josef Klumpen
Registry Australian New Zealand Clinical Trials Registry (ANZCTR)
Recruitment status Not Recruiting
Study type Observational
Phase Not Applicable
Countries Australia
Conditions Patients revieving treatment with imatinib, currently CML (Chronic Myeloid Leukaemia) and GIST (Gastro-Intestinal Stromal Tumour); Patients revieving treatment with imatinib, currently CML (Chronic Myeloid Leukaemia) and GIST…
Interventions The study will correlate the toxicity-adjusted dose of imatinib after 3 months of therapy with polymorphisms of drug elimination genes, particularly ABCB1 (MDR1). Patients will be asked to give a single blood sample for genotyping (at any…
Registration date Mar 4, 2006
Target size 300
Secondary IDs HGWH0006
Registry page anzctr.org.au

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Source: World Health Organization (WHO), International Clinical Trials Registry Platform (ICTRP) · Source date:

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