Article
A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA…
medRxiv · 2024 · Tilley, L.; Xie, S. C.; Tai, C.-W.; Morton, C. J.; Ma, L.; Huang, S.-C.; Wittlin, S.; Du, Y.; Hu, Y.; Dogovski, C.; Salimimarand, M.; Griffin, R.; England, D.; de la Curz, E.; Deni, I.; Yeo, T.; Burkhard, A. Y.; Striepen, J.; Schindler, K. A.; Crespo, B.; Gamo, F. J.; Khandokar, Y.; Hutton, C. A.; Rabie, T.; Birkholtz, L.-M.; Famodimu, M. T.; Delves, M. J.; Bolsher, J.; Koolen, K. M. J.; van der Laak, R.; Aguiar, A. C. C.; Pereira, D. B.; Creek, D. J.; Fidock, D. A.; Dick, L. R.; Brand, S. L.; Gould, A. E.; Langston, S.; Griffin, M. D. W.
Key facts
| Title | A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo |
|---|---|
| First author | Tilley, L.; Xie, S. C.; Tai, C.-W.; Morton, C. J.; Ma, L.; Huang, S.-C.; Wittlin, S.; Du, Y.; Hu, Y.; Dogovski, C.; Salimimarand, M.; Griffin, R.; England, D.; de la Curz, E.; Deni, I.; Yeo, T.; Burkhard, A. Y.; Striepen, J.; Schindler, K. A.; Crespo, B.; Gamo, F. J.; Khandokar, Y.; Hutton, C. A.; Rabie, T.; Birkholtz, L.-M.; Famodimu, M. T.; Delves, M. J.; Bolsher, J.; Koolen, K. M. J.; van der Laak, R.; Aguiar, A. C. C.; Pereira, D. B.; Creek, D. J.; Fidock, D. A.; Dick, L. R.; Brand, S. L.; Gould, A. E.; Langston, S.; Griffin, M. D. W. |
| Journal | medRxiv |
| Published | Jan 1, 2024 |
| DOI | 10.1101/2024.07.22.604682 |
| Devices mentioned | K042152, K940422, K982100 |
| Product codes mentioned | CFN, DFZ, JJQ, JQW, NJT |
At a glance
- 1–9 FDA submissions mentioned
- 1–9 Product codes mentioned
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About Literature
Peer-reviewed and preprint literature indexed by Orca1 and linked to the FDA submissions and product codes each article mentions. Only bibliographic details are shown here.
Source: Publisher and PubMed metadata; device mentions identified by Orca1