Article

Pathological mutations reveal the key role of the iRhom2 N-terminus for ADAM17 binding…

medRxiv · 2023 · Bläsius, K.; Ludwig, L.; Knapp, S.; Flasshove, C.; Sonnabend, F.; Keller, D.; Tacken, N.; Gao, X.; Kahveci, S.; Grannemann, C.; Babendreyer, A.; Adrain, C.; Huth, S.; Baron, J.; Ludwig, A.; Düsterhöft, S.

Key facts

Title Pathological mutations reveal the key role of the iRhom2 N-terminus for ADAM17 binding, stability and activity.
First author Bläsius, K.; Ludwig, L.; Knapp, S.; Flasshove, C.; Sonnabend, F.; Keller, D.; Tacken, N.; Gao, X.; Kahveci, S.; Grannemann, C.; Babendreyer, A.; Adrain, C.; Huth, S.; Baron, J.; Ludwig, A.; Düsterhöft, S.
Journal medRxiv
Published Nov 27, 2023
DOI 10.1101/2023.08.31.555720
Devices mentioned K914390
Product codes mentioned DDG, JCJ, JJH

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  • 1–9 FDA submissions mentioned
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