Article
Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal…
medRxiv · 2024 · Wei, S.; Cantor, A. J.; Walleshauser, J.; Mepani, R.; Melton, K.; Bans, A.; Khekare, P.; Gupta, S.; Wang, J.; Soares, C.; Kiwan, R.; Lee, J.; McCawley, S.; Jani, V.; Leong, W. I.; Shahi, P. K.; Chan, J.; Boivin, P.; Otoupal, P.; Pattnaik, B. R.; Gamm, D. M.; Saha, K.; Gowen, B. G.; Haak-Frendscho, M.; Janatpour, M. J.; Silverman, A. P.
Key facts
| Title | Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines |
|---|---|
| First author | Wei, S.; Cantor, A. J.; Walleshauser, J.; Mepani, R.; Melton, K.; Bans, A.; Khekare, P.; Gupta, S.; Wang, J.; Soares, C.; Kiwan, R.; Lee, J.; McCawley, S.; Jani, V.; Leong, W. I.; Shahi, P. K.; Chan, J.; Boivin, P.; Otoupal, P.; Pattnaik, B. R.; Gamm, D. M.; Saha, K.; Gowen, B. G.; Haak-Frendscho, M.; Janatpour, M. J.; Silverman, A. P. |
| Journal | medRxiv |
| Published | Jan 1, 2024 |
| DOI | 10.1101/2024.12.30.630799 |
| Devices mentioned | K101223, K113129, K121993, K152205, K172649, K173648, K181594, K182569, K192391, K201252, K223557, K240221 and 3 more |
| Product codes mentioned | EWY, GCJ, OBO, HOO, MYC, HYJ, JCC, JJQ, JQW, MXK, HPT, NJT and 1 more |
At a glance
- 10–99 FDA submissions mentioned
- 10–99 Product codes mentioned
Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.
About Literature
Peer-reviewed and preprint literature indexed by Orca1 and linked to the FDA submissions and product codes each article mentions. Only bibliographic details are shown here.
Source: Publisher and PubMed metadata; device mentions identified by Orca1