Article

Rational design of potent small molecule SMARCA2/A4 (BRM/BRG1) degraders acting via the…

medRxiv · 2025 · Villemure, E.; Yauch, R. L.; Rudolph, J.; Januario, T.; Zeng, M.; Budayeva, H. G.; Walters, B. T.; Lictao, A.; Li, S. K.; Ye, X.; Gilchrist, C. L.; Hoag, B.; Endres, N. F.; Hsu, P. L.; Chan, J.; Cheung, T. K.; Costa, M. R.; Fortin, J.-P.; Ishisoko, N.; Babin, B. M.; Liu, J.

Key facts

Title Rational design of potent small molecule SMARCA2/A4 (BRM/BRG1) degraders acting via the recruitment of FBXO22
First author Villemure, E.; Yauch, R. L.; Rudolph, J.; Januario, T.; Zeng, M.; Budayeva, H. G.; Walters, B. T.; Lictao, A.; Li, S. K.; Ye, X.; Gilchrist, C. L.; Hoag, B.; Endres, N. F.; Hsu, P. L.; Chan, J.; Cheung, T. K.; Costa, M. R.; Fortin, J.-P.; Ishisoko, N.; Babin, B. M.; Liu, J.
Journal medRxiv
Published Jan 1, 2025
DOI 10.1101/2025.03.05.641484
Devices mentioned 207146, K790117, K864267
Product codes mentioned DPM, JXR, JJH, PFT

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  • 1–9 FDA submissions mentioned
  • 1–9 Product codes mentioned

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