Article
Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms…
medRxiv · 2024 · Kwon, J.; Dilly, J.; Liu, S.; Kim, E.; Bian, Y.; Dharmaiah, S.; Tran, T. H.; Kapner, K. S.; Ly, S. H.; Yang, X.; Rabara, D.; Waybright, T. J.; Giacomelli, A. O.; Hong, A. L.; Misek, S. L.; Wang, B.; Ravi, A.; Beroukhim, R.; Lemke, C. T.; Haigis, K. M.; Esposito, D.; Root, D. E.; Nissley, D. V.; Stephen, A. G.; McCormick, F.; Simanshu, D. K.; Hahn, W. C.; Aguirre, A. J.
Key facts
| Title | Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity |
|---|---|
| First author | Kwon, J.; Dilly, J.; Liu, S.; Kim, E.; Bian, Y.; Dharmaiah, S.; Tran, T. H.; Kapner, K. S.; Ly, S. H.; Yang, X.; Rabara, D.; Waybright, T. J.; Giacomelli, A. O.; Hong, A. L.; Misek, S. L.; Wang, B.; Ravi, A.; Beroukhim, R.; Lemke, C. T.; Haigis, K. M.; Esposito, D.; Root, D. E.; Nissley, D. V.; Stephen, A. G.; McCormick, F.; Simanshu, D. K.; Hahn, W. C.; Aguirre, A. J. |
| Journal | medRxiv |
| Published | Jan 1, 2024 |
| DOI | 10.1101/2024.10.22.618529 |
| Devices mentioned | 210519, BK110039, K103302, K831329 |
| Product codes mentioned | CIT, HAW, KIT, MVU, NDS, NJT, OOI, PFT, PCA |
At a glance
- 1–9 FDA submissions mentioned
- 1–9 Product codes mentioned
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