Article

Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib…

Drug Design, Development and Therapy · 2015 · Niu NK, Wang ZL, Pan ST, Ding HQ, Au GHT, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF

Key facts

Title Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway
First author Niu NK, Wang ZL, Pan ST, Ding HQ, Au GHT, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF
Journal Drug Design, Development and Therapy
Published Mar 12, 2015
DOI 10.2147/DDDT.S74197
Devices mentioned K810863, K973350, K990827
Product codes mentioned DBM, JLX, KQP

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  • 1–9 FDA submissions mentioned
  • 1–9 Product codes mentioned

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