Article

Inhibition of PIKfyve kinase induces senescent cell death by suppressing lysosomal…

medRxiv · 2025 · Barkovskaya, A.; Kim, K.; Shankar, A.; Meca-Laguna, G.; Rae, M.; Le Saux, C. J.; Sharma, A.

Key facts

Title Inhibition of PIKfyve kinase induces senescent cell death by suppressing lysosomal exocytosis and leads to improved outcomes in a mouse model of idiopathic pulmonary fibrosis
First author Barkovskaya, A.; Kim, K.; Shankar, A.; Meca-Laguna, G.; Rae, M.; Le Saux, C. J.; Sharma, A.
Journal medRxiv
Published Jan 1, 2025
DOI 10.1101/2025.03.19.644224
Devices mentioned K202641, K231013, K802418, K973350, K990827
Product codes mentioned JCJ, MVU, JLX, KIS, KQP, QBD

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  • 1–9 FDA submissions mentioned
  • 1–9 Product codes mentioned

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