Clinical trial

Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for…

NCT02490878 · Alliance for Clinical Trials in Oncology, Other · Terminated

Key facts

NCT number NCT02490878
Title Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases
Official title Randomized Phase II Study: Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases
Lead sponsor Alliance for Clinical Trials in Oncology, Other
Collaborators National Cancer Institute (NCI) NIH Genentech, Inc. Industry
Status Terminated
Phase Phase 2
Study type Interventional
Conditions Radionecrosis, Brain Metastases
Intervention type Drug, Other
Interventions bevacizumab, corticosteroids, placebo
Enrollment 19
Start date Apr 1, 2016
Primary completion Feb 1, 2019
Completion Dec 15, 2022
First posted Jul 7, 2015
Last update posted Mar 23, 2023
Countries Canada, United States

At a glance

  • 100–999 Study sites
  • Yes Results posted
  • None Linked FDA submissions

Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.

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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date:

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