Clinical trial
Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With…
NCT00499369 · National Cancer Institute (NCI), NIH · Terminated
Key facts
| NCT number | NCT00499369 |
|---|---|
| Title | Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer That Progressed During First-Line Therapy |
| Official title | Phase III Trial of Irinotecan-Based Chemotherapy Plus Cetuximab (NSC-714692) or Bevacizumab (NSC-704865) as Second-Line Therapy for Patients With Metastatic Colorectal Cancer Who Have Progressed on Bevacizumab With Either FOLFOX, OPTIMOX or XELOX |
| Lead sponsor | National Cancer Institute (NCI), NIH |
| Collaborators | North Central Cancer Treatment Group Cancer and Leukemia Group B Eastern Cooperative Oncology Group NCIC Clinical Trials Group |
| Status | Terminated |
| Phase | Phase 3 |
| Study type | Interventional |
| Conditions | Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IVA Colon Cancer, Stage IVA Rectal Cancer, Stage IVB Colon Cancer, Stage IVB Rectal Cancer |
| Intervention type | Biological, Drug |
| Interventions | irinotecan hydrochloride, leucovorin calcium, fluorouracil, cetuximab, bevacizumab |
| Enrollment | 72 |
| Start date | Jun 1, 2007 |
| Primary completion | Nov 1, 2012 |
| Completion | Nov 1, 2012 |
| First posted | Jul 11, 2007 |
| Last update posted | Jul 31, 2014 |
| Countries | United States |
At a glance
- 100–999 Study sites
- Yes Results posted
- None Linked FDA submissions
Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.
About ClinicalTrials.gov studies
ClinicalTrials.gov is the U.S. National Library of Medicine's registry of clinical studies conducted around the world. Contact and investigator details are not shown here.
Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date: