Clinical trial
Differential Adrenoreceptor Mediated Tachyphylaxis and Upregulation
NCT00487032 · Brian J Lipworth, Other · Completed
Key facts
| NCT number | NCT00487032 |
|---|---|
| Title | Differential Adrenoreceptor Mediated Tachyphylaxis and Upregulation |
| Official title | A Proof of Concept Study to Evaluate Differential Tachyphylaxis of Alpha 1 and Alpha 2 Adrenoreceptor Mediated Decongestant Response to Oxymetazoline and Its Acute Reversal by Corticosteroid in Healthy Volunteers |
| Lead sponsor | Brian J Lipworth, Other |
| Status | Completed |
| Phase | Phase 4 |
| Study type | Interventional |
| Conditions | Allergic Rhinitis, Tachyphylaxis, Rhinitis Medicamentosa |
| Intervention type | Drug |
| Interventions | Oxymetazoline 0.05% w/v, Fluticasone propionate 50 micrograms per actuation, Prazosin hydrochloride, Placebo to Prazosin |
| Enrollment | 19 |
| Start date | May 1, 2008 |
| Primary completion | May 1, 2009 |
| Completion | May 1, 2009 |
| First posted | Jun 15, 2007 |
| Last update posted | Apr 12, 2019 |
| Countries | United Kingdom |
At a glance
- 1–9 Study sites
- No Results posted
- None Linked FDA submissions
Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.
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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date: