Clinical trial

Effect of Pegvisomant on GH/IGF-I Relationship in GHD

NCT00468624 · The Christie NHS Foundation Trust, Other · Terminated

Key facts

NCT number NCT00468624
Title Effect of Pegvisomant on GH/IGF-I Relationship in GHD
Official title A Study of the Relationship Between Serum Growth Hormone (GH) and Insulin-Like Growth Factor One (IGF-I) in Patients With Severe Adult Growth Hormone Deficiency (AGHD)
Lead sponsor The Christie NHS Foundation Trust, Other
Status Terminated
Study type Interventional
Conditions Severe Adult Growth Hormone Deficiency
Intervention type Drug, Procedure
Interventions pegvisomant/placebo loading dose 80mg sc, thereafter 20mg daily for 2 weeks, GH sampling - every 20 min over 24 hours after each limb (pegvisomant/placebo), blood sampling before and after pegvisomant/placebo, arginine stimulation test after each limb
Start date Dec 1, 2004
Completion Jul 1, 2005
First posted May 3, 2007
Last update posted May 3, 2007
Countries United Kingdom

At a glance

  • 1–9 Study sites
  • No Results posted
  • None Linked FDA submissions

Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.

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