Clinical trial

Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria

NCT00425607 · Monica E. Kleinman, Other · Completed

Key facts

NCT number NCT00425607
Title Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria
Official title An Open Label Dose Adjusted Phase II Trial of the Oral Farnesyltransferase Inhibitor (FTI) Lonafarnib (SCH66336) for Patients With Hutchinson-Gilford Progeria Syndrome (HGPS) and Progeroid Laminopathies
Lead sponsor Monica E. Kleinman, Other
Collaborators Schering-Plough Industry
Status Completed
Phase Phase 2
Study type Interventional
Conditions Progeria, Hutchinson-Gilford Syndrome
Intervention type Drug
Interventions Lonafarnib
Enrollment 29
Start date May 1, 2007
Primary completion Oct 1, 2009
Completion Oct 1, 2009
First posted Jan 23, 2007
Last update posted Jun 25, 2019
Countries United States

At a glance

  • 1–9 Study sites
  • Yes Results posted
  • None Linked FDA submissions

Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.

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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date:

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