Clinical trial
Clofarabine, Melphalan, and Thiotepa Followed By a Donor Stem Cell Transplant in…
NCT00423514 · Memorial Sloan Kettering Cancer Center, Other · Completed
Key facts
| NCT number | NCT00423514 |
|---|---|
| Title | Clofarabine, Melphalan, and Thiotepa Followed By a Donor Stem Cell Transplant in Treating Patients With High-Risk and/or Advanced Hematologic Cancer or Other Disease |
| Official title | A Phase I/II Dose Escalation Trial of Clofarabine, in Addition to Melphalan and Thiotepa as Myeloablative Regimen Followed by an Allogeneic Unmodified Hematopoietic Stem Cell Transplant From HLA-Compatible Related or Unrelated Donors for the Treatment of High Risk and/or Advanced Hematologic… |
| Lead sponsor | Memorial Sloan Kettering Cancer Center, Other |
| Collaborators | National Cancer Institute (NCI) NIH |
| Status | Completed |
| Phase | Phase 1/Phase 2 |
| Study type | Interventional |
| Conditions | Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes |
| Intervention type | Biological, Drug, Procedure |
| Interventions | filgrastim, clofarabine, melphalan, mycophenolate mofetil, tacrolimus, thiotepa, allogeneic bone marrow transplantation, allogeneic hematopoietic stem cell transplantation, peripheral blood stem cell transplantation |
| Enrollment | 38 |
| Start date | Nov 20, 2006 |
| Primary completion | Jun 18, 2021 |
| Completion | Jun 18, 2021 |
| First posted | Jan 18, 2007 |
| Last update posted | Dec 27, 2022 |
| Countries | United States |
At a glance
- 1–9 Study sites
- Yes Results posted
- None Linked FDA submissions
Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.
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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date: