Clinical trial

An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer

NCT00410761 · Genzyme, a Sanofi Company, Industry · Completed

Key facts

NCT number NCT00410761
Title An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer
Official title An International, Phase III, Randomized, Double-Blinded, Placebo-Controlled, Multi-Center Study to Assess the Efficacy of ZD6474 (ZACTIMATM) Versus Placebo in Subjects With Unresectable Locally Advanced or Metastatic Medullary Thyroid Cancer
Lead sponsor Genzyme, a Sanofi Company, Industry
Status Completed
Phase Phase 3
Study type Interventional
Conditions Thyroid Cancer
Intervention type Drug
Interventions ZD6474 (Vandetanib)
Enrollment 331
Start date Nov 23, 2006
Primary completion Jul 31, 2009
Completion Jul 26, 2024
First posted Dec 13, 2006
Last update posted Sep 24, 2025
Countries Australia, Austria, Belgium, Brazil, Canada, Czechia, Denmark, France, Germany, Hungary, India, Italy and 12 more

At a glance

  • 100–999 Study sites
  • Yes Results posted
  • None Linked FDA submissions

Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.

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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date:

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