Clinical trial
Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral…
NCT00397813 · Fred Hutchinson Cancer Center, Other · Completed
Key facts
| NCT number | NCT00397813 |
|---|---|
| Title | Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders |
| Official title | Low-Dose TBI Dose Escalation to Decrease Risks of Progression and Graft Rejection After Hematopoietic Cell Transplantation With Nonmyeloablative Conditioning as Treatment for Untreated Myelodysplastic Syndrome or Myeloproliferative Disorders - A Multi-Center Trial |
| Lead sponsor | Fred Hutchinson Cancer Center, Other |
| Collaborators | National Cancer Institute (NCI) NIH National Heart, Lung, and Blood Institute (NHLBI) |
| Status | Completed |
| Phase | Phase 2 |
| Study type | Interventional |
| Conditions | Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndrome, Essential Thrombocythemia, Myeloproliferative Neoplasm, Paroxysmal Nocturnal Hemoglobinuria, Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase, Primary Myelofibrosis and 5 more |
| Intervention type | Drug, Other, Procedure, Radiation |
| Interventions | Cyclosporine, Fludarabine Phosphate, Laboratory Biomarker Analysis, Mycophenolate Mofetil, Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation, Peripheral Blood Stem Cell Transplantation, Total-Body Irradiation |
| Enrollment | 77 |
| Start date | Jan 1, 2006 |
| Primary completion | Sep 1, 2017 |
| Completion | Mar 1, 2018 |
| First posted | Nov 10, 2006 |
| Last update posted | Jan 31, 2020 |
| Countries | United States |
At a glance
- 1–9 Study sites
- Yes Results posted
- None Linked FDA submissions
Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.
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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date: