Clinical trial

Bevacizumab, Sorafenib Tosylate, and Temsirolimus in Treating Patients With…

NCT00378703 · National Cancer Institute (NCI), NIH · Completed

Key facts

NCT number NCT00378703
Title Bevacizumab, Sorafenib Tosylate, and Temsirolimus in Treating Patients With Metastatic Kidney Cancer
Official title The BeST Trial: A Randomized Phase II Study of VEGF, RAF Kinase, and mTOR Combination Targeted Therapy (CTT) With Bevacizumab, Sorafenib, and Temsirolimus in Advanced Renal Cell Carcinoma
Lead sponsor National Cancer Institute (NCI), NIH
Status Completed
Phase Phase 2
Study type Interventional
Conditions Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Carcinoma, Stage IV Renal Cell Cancer AJCC v7
Intervention type Biological, Drug, Other
Interventions Bevacizumab, Laboratory Biomarker Analysis, Pharmacological Study, Sorafenib Tosylate, Temsirolimus
Enrollment 361
Start date Sep 14, 2007
Primary completion Feb 7, 2014
Completion Mar 21, 2017
First posted Sep 21, 2006
Last update posted Nov 14, 2018
Countries Peru, United States

At a glance

  • 100–999 Study sites
  • Yes Results posted
  • None Linked FDA submissions

Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.

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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date:

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