Clinical trial

Effects of Thiazide Diuretics on Sympathetic Nervous System in Hypertension

NCT00353652 · University of Texas Southwestern Medical Center, Other · Completed

Key facts

NCT number NCT00353652
Title Effects of Thiazide Diuretics on Sympathetic Nervous System in Hypertension
Official title Neural Mechanisms of Thiazide-induced Insulin Resistance
Lead sponsor University of Texas Southwestern Medical Center, Other
Collaborators National Heart, Lung, and Blood Institute (NHLBI) NIH
Status Completed
Phase Phase 4
Study type Interventional
Conditions Hypertension
Intervention type Drug
Interventions Study#1: chlorthalidone (CTD), titrated dose, Study #1: spironolactone (SP), Study# 2 chlorthalidone (CTD), fixed dose, Study# 2 spironolactone (SP), Study# 2 irbsesartan (IR)
Enrollment 166
Start date Jan 1, 2005
Primary completion Jan 1, 2013
Completion Jan 1, 2013
First posted Jul 19, 2006
Last update posted Feb 6, 2019
Countries United States

At a glance

  • 1–9 Study sites
  • Yes Results posted
  • None Linked FDA submissions

Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.

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