Clinical trial
IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin…
NCT00202878 · Organon and Co, Industry · Completed
Key facts
| NCT number | NCT00202878 |
|---|---|
| Title | IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin (Ezetimibe/Simvastatin) vs Simvastatin (P04103) |
| Official title | A Multicenter, Double-Blind, Randomized Study to Establish the Clinical Benefit and Safety of Vytorin (Ezetimibe/Simvastatin Tablet) vs Simvastatin Monotherapy in High-Risk Subjects Presenting With Acute Coronary Syndrome (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial… |
| Lead sponsor | Organon and Co, Industry |
| Status | Completed |
| Phase | Phase 3 |
| Study type | Interventional |
| Conditions | Hypercholesterolemia, Myocardial Infarction |
| Intervention type | Drug |
| Interventions | ezetimibe/simvastatin, simvastatin, Placebo for simvastatin 40 mg, Placebo for ezetimibe 10 mg/simvastatin 40 mg combination |
| Enrollment | 18,144 |
| Start date | Oct 17, 2005 |
| Primary completion | Sep 18, 2014 |
| Completion | Sep 18, 2014 |
| First posted | Sep 20, 2005 |
| Last update posted | Jun 18, 2024 |
At a glance
- Yes Results posted
- 1–9 Linked FDA submissions
Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.
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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date: