Clinical trial
Avoiding Cardiovascular Events Through Combination Therapy in Patients Living…
NCT00170950 · Novartis, Industry · Terminated
Key facts
| NCT number | NCT00170950 |
|---|---|
| Title | Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension |
| Official title | A Prospective, Multinational, Multicenter Trial to Compare the Effects of Amlodipine/Benazepril to Benazepril and Hydrochlorothiazide Combined on the Reduction of Cardiovascular Morbidity and Mortality in Patients With High Risk Hypertension |
| Acronym | ACCOMPLISH |
| Lead sponsor | Novartis, Industry |
| Status | Terminated |
| Phase | Phase 3 |
| Study type | Interventional |
| Conditions | Hypertension |
| Intervention type | Drug |
| Interventions | Benazepril/amlodipine 20/5 mg - Dose Level 1 from Day 1 to Month 1, Benazepril/amlodipine 40/5 mg - Dose Level 2 from Month 1 to Month 2, Benazepril/amlodipine 40/10 mg - Dose Level 3 from Month 2 to Month 3 and thereafter, Benazepril/hydrochlorothiazide 20/12.5 mg - Dose Level 1 from Day 1 to Month 1, Benazepril/hydrochlorothiazide 40/12.5 mg - Dose Level 2 from Month 1 to Month 2, Benazepril/hydrochlorothiazide 40/25 mg - Dose Level 3 from Month 2 to Month 3 and thereafter |
| Enrollment | 11,506 |
| Start date | Oct 1, 2003 |
| Primary completion | Jan 1, 2008 |
| Completion | May 1, 2008 |
| First posted | Sep 15, 2005 |
| Last update posted | Oct 24, 2023 |
| Countries | Denmark, Finland, Norway, Sweden, United States |
At a glance
- 1–9 Study sites
- Yes Results posted
- None Linked FDA submissions
Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.
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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date: