Clinical trial

A Notch Signalling Pathway Inhibitor for Patients With Advanced Breast Cancer…

NCT00106145 · Merck Sharp & Dohme LLC, Industry · Completed

Key facts

NCT number NCT00106145
Title A Notch Signalling Pathway Inhibitor for Patients With Advanced Breast Cancer (0752-014)
Official title A Phase I Study of MK0752, a Notch Inhibitor, in Patients With Metastatic or Locally Advanced Breast Cancer and Other Solid Tumors
Lead sponsor Merck Sharp & Dohme LLC, Industry
Status Completed
Phase Phase 1
Study type Interventional
Conditions Advanced Breast Cancer, Other Solid Tumors
Intervention type Drug
Interventions Comparator: MK0752, Notch Inhibitor, Notch Inhibitor - 450 mg, Notch Inhibitor - 3 days on, 4 off, Notch Inhibitor - 1 day on, 6 off, 4 off 350 mg
Enrollment 103
Start date Apr 1, 2005
Primary completion Aug 1, 2011
Completion Aug 1, 2011
First posted Mar 22, 2005
Last update posted Jan 30, 2015

At a glance

  • No Results posted
  • None Linked FDA submissions

Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.

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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date:

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