Clinical trial

MS-275 and Azacitidine in Treating Patients With Myelodysplastic Syndromes…

NCT00101179 · National Cancer Institute (NCI), NIH · Completed

Key facts

NCT number NCT00101179
Title MS-275 and Azacitidine in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia
Official title A Dose-Finding Trial of the Histone Deacetylase Inhibitor MS-275 (NSC 706995) in Combination With 5-Azacitidine (5AC, NSC 102816) in Patients With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMMoL) and Acute Myeloid Leukemia (AML)
Lead sponsor National Cancer Institute (NCI), NIH
Status Completed
Phase Phase 1
Study type Interventional
Conditions Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndrome, Leukemia, Myelodysplastic Syndrome, Recurrent Adult Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndrome
Intervention type Drug
Interventions Azacitidine, Entinostat
Enrollment 63
Start date Nov 3, 2004
Primary completion Apr 20, 2011
Completion Feb 3, 2014
First posted Jan 10, 2005
Last update posted Oct 18, 2019
Countries United States

At a glance

  • 1–9 Study sites
  • No Results posted
  • None Linked FDA submissions

Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.

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