Clinical trial
Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus…
NCT00074490 · National Cancer Institute (NCI), NIH · Terminated
Key facts
| NCT number | NCT00074490 |
|---|---|
| Title | Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers |
| Official title | Allogeneic HSCT Without Preparative Chemotherapy or With Low-Intensity Preparative Chemotherapy Using Sirolimus and Sirolimus-Generated Donor Th2 Cells for Therapy of Refractory Leukemia, Lymphoma, Myeloma, or Myelodysplastic Syndrome |
| Lead sponsor | National Cancer Institute (NCI), NIH |
| Status | Terminated |
| Phase | Phase 2 |
| Study type | Interventional |
| Conditions | Lymphoma, Leukemia, Myeloproliferative Disorders, Multiple Myleoma, Myelodysplastic Syndrome |
| Intervention type | Drug, Genetic, Procedure |
| Interventions | Rituximab, Fludarabine, Etoposide, Doxorubicin, Vincristine, Cyclophosphamide, Peripheral blood stem cell (PBSC) transplantation, T cell donor lymphocyte infusion (DLI) with unmanipulated donor T cells, Prednisone, Allogeneic hematopoietic stem cell transplant (HSCT) and 2 more |
| Enrollment | 442 |
| Start date | Jan 1, 2004 |
| Primary completion | Jul 20, 2017 |
| Completion | Aug 16, 2017 |
| First posted | Dec 15, 2003 |
| Last update posted | Dec 31, 2018 |
| Countries | United States |
At a glance
- 1–9 Study sites
- Yes Results posted
- None Linked FDA submissions
Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.
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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date: