Clinical trial

Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating…

NCT00043004 · European Organisation for Research and Treatment of Cancer - EORTC, Other · Terminated

Key facts

NCT number NCT00043004
Title Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating Unresectable Liver Metastases in Patients With Colorectal Cancer
Official title CLOCC Trial (Chemotherapy + Local Ablation Versus Chemotherapy) Randomized Phase II Study Of Local Treatment Of Liver Metastases By Radiofrequency Combined With Chemotherapy Versus Chemotherapy Alone In Patients With Unresectable Colorectal Liver Metastases
Lead sponsor European Organisation for Research and Treatment of Cancer - EORTC, Other
Collaborators Arbeitsgruppe Lebermetastasen und Tumoren Institute of Cancer Research, United Kingdom
Status Terminated
Phase Phase 2
Study type Interventional
Conditions Colorectal Cancer, Metastatic Cancer
Intervention type Biological, Drug, Procedure
Interventions bevacizumab, FOLFOX regimen, fluorouracil, leucovorin calcium, oxaliplatin, conventional surgery, radiofrequency ablation
Enrollment 119
Start date May 1, 2002
Primary completion Jun 1, 2007
First posted Jan 27, 2003
Last update posted Sep 24, 2012
Countries Austria, Belgium, Egypt, France, Germany, Hungary, Italy, Netherlands, Sweden, United Kingdom

At a glance

  • 10–99 Study sites
  • No Results posted
  • None Linked FDA submissions

Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.

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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date:

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