Clinical trial
Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors
NCT00005796 · Indiana University, Other · Completed
Key facts
| NCT number | NCT00005796 |
|---|---|
| Title | Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors |
| Official title | A Pilot Study of Dose-Intensified Procarbazine, CCNU, Vincristine (PCV) for Poor Prognosis Pediatric and Adult Brain Tumors Utilizing Fibronectin-Assisted, Retroviral-Mediated Modification of CD34+ Peripheral Blood Cells With O6-Methylguanine DNA Methyltransferase |
| Lead sponsor | Indiana University, Other |
| Collaborators | Indiana University Melvin and Bren Simon Cancer Center |
| Status | Completed |
| Phase | Phase 1 |
| Study type | Interventional |
| Conditions | Bone Marrow Suppression, Brain and Central Nervous System Tumors, Drug/Agent Toxicity by Tissue/Organ |
| Intervention type | Biological, Drug, Procedure |
| Interventions | filgrastim, gene therapy, lomustine, procarbazine hydrochloride, vincristine sulfate, in vitro-treated peripheral blood stem cell transplantation |
| Enrollment | 10 |
| Start date | Feb 1, 2000 |
| Primary completion | Jun 1, 2003 |
| Completion | Dec 1, 2011 |
| First posted | Apr 28, 2004 |
| Last update posted | Mar 25, 2015 |
| Countries | United States |
At a glance
- 1–9 Study sites
- No Results posted
- None Linked FDA submissions
Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.
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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date: