Clinical trial
Radiation Therapy Combined With Chemotherapy in Treating Patients With…
NCT00004259 · Radiation Therapy Oncology Group, Other · Completed
Key facts
| NCT number | NCT00004259 |
|---|---|
| Title | Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed Gliomas |
| Official title | A Phase III Randomized Study (Phase I Closed) of Radiation Therapy and Temozolomide Versus Radiation Therapy and Nitrosourea for Anaplastic Astrocytoma And Mixed Anaplastic Oligoastrocytoma (Astrocytoma Dominant) |
| Lead sponsor | Radiation Therapy Oncology Group, Other |
| Collaborators | National Cancer Institute (NCI) NIH North Central Cancer Treatment Group Eastern Cooperative Oncology Group NRG Oncology |
| Status | Completed |
| Phase | Phase 3 |
| Study type | Interventional |
| Conditions | Brain and Central Nervous System Tumors |
| Intervention type | Drug, Radiation |
| Interventions | BCNU 80mg/m2, TMZ 200mg/m2, radiation therapy, CCNU, BCNU 150mg/m2, BCNU 200mg/m2, TMZ 150mg/m2 six 6-week cycles, TMZ 150mg/m2 six 8-week cycles |
| Enrollment | 230 |
| Start date | Jun 1, 2000 |
| Primary completion | Feb 1, 2015 |
| Completion | May 14, 2018 |
| First posted | Jan 27, 2003 |
| Last update posted | Sep 12, 2019 |
| Countries | United States |
At a glance
- 10–99 Study sites
- Yes Results posted
- 1–9 Linked FDA submissions
Counts are shown as ranges. Exact figures, trends and every underlying record are available in Orca1.
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Source: U.S. National Library of Medicine (NLM), ClinicalTrials.gov · Source date: